Before the whole hands debacle, Margarito was one of my favorite fighters, there was a time when almost everyone in the welterweight division ducked him, and for good reason (at the time). Apparently, he offered "The Coward" his biggest payday at the time, and as usual, he ducked Margarito (and it had nothing to do with the loaded gloves, no one even knew of/suspected that at the time). Margarito's style is awkward, and before the Mosley fight, he had shown an uncanny ability to walk down opponents even when he is getting hit with a barrage of shots. People can say what they want to about whether or not he was loading his gloves, but in that Cotto fight Margarito simply broke Cotto's spirit by walking down shots that would have KO'd other fighters.
Margarito will not be a pushover, but I do wonder about his overall mental state after the whole plaster in the gloves deal. I think it will be a decent fight, but after seeing what Mosley did to Margarito, I don't see how he can beat Manny....then again, you never know.