Yes. Whatever(everything if you like) you want the CPU to handle...give those teams a profile with those options/tasks set to AUTO.
Note: You can STILL step in and make decisions for the "CPU" controlled teams WITHOUT having to change the profile...just do it(trades/releases/signings/offers...etc) You will have to change lineups/rotations to MANUAL if you want to have those not change...they will change it back otherwise(also..the CPU will always sub for fatigue...regardless)
Thanks Brett!
M.K.
Knight165