Updated 3/2/2014
I've been reading the threads on here, and tried to incorporate what I felt was the best from all the "gurus" to create a set that has been enjoyable to play with. I started with the penalties first to try and nail the gameplay down and then worked on sliders from there. Settings are the same for HUM and CPU.
Gameplay
Skill Level - All-Madden
Quarter Length - 15 Min
Playcall Stye - Conventional
Play Clock - On
Accelerated Clock - On
Minimum Play Clock Time - 15 seconds
Camera Settings - Zoomed
Auto Strafe - Off
Heat Seeker - Off
Ball Hawk - Off
Switch Assist - Off
Injuries - 35
Fatigue - 40
Game Speed - Slow
Threshold - 0
Penalties
Offside 65
False start 50
Holding 55
Facemask 30
DPI 55
OPI 55
KR/PR Int 40
Clipping 55
Int Grounding 40
RTP 45
RTK 65
Sliders
QBA 5
Pass Blk 0
WR Catch 45
Run Blk 0
Fumbles 30
Reaction Time 40
Interception 15
Pass Coverage 0
Tackling 45
Special Teams
FG Power 50
FG Accuracy 35
Punt Power 45
Punt Accuracy 85
Kickoff Power 55
Auto-Subs
QB 25/20
RB 85/80
WR 65/60
FB/TE 65/60
OL 25/20
DT 85/80
DE 85/80
LB 75/70
CB 65/60
S 65/60