I posted this in the impressions thread but it's valid for here more:
http://theshownation.com/bug_reports/10566
I am not one to criticize others work and I do not know all of the details of the coding process but it would seem important enough to look into changing some variables to at least dampen the amount of pickoffs you see. Attention to details is important, We are seeing an exorbitant amount of pickoffs even with no lead taken, that should not be happening. Considering how closely the game follows real life numbers in terms of strike % in every count, doubles, triples, homers, strikeouts the steals and pickoffs being not even close to real life stands out more.
To be clear I am talking about non-rtts games with stock rosters. I could see getting picked off in rtts just because your guy is low rated but this happens way out of proportion in the normal game and it shouldn't be. It happens to both the CPU and the user (autobaserunning). The pickoff slider only affects frequency but that still is not enough and you still see weird outcomes to guys being picked off with default leads.