As in Live 10 then 2k11 they would lose the ball dribbling into traffic but I don't think it was done too well... I dont like the picking up the ball option honestly.
Dribbling alot though....
#1 it should tire you out as in real life, which leads to slower dribbling, prone to mistakes and,
#2 just a ton of stationary dribbling should increase the chance of getting stripped doubled or cause a break down in the offense similar to how you break freelance if you don't pass the ball within 2 seconds.
#3 back to #1 it should affect your shot. Only the best of those can do that stuff, and even then they dont always do it... would definitely make you think about moving the ball more for good shots.