I stopped loading up the game human vs cpu mode because it felt like once you switched it over to CPU vs CPU mode after the kickoff the human selected team still had some kind of advantage programmed in.
So for the past month while tweaking the sliders I've selected CPU vs CPU gameplay right from the start.
It stops me from setting the strategy before games now because I used to love putting Big Hits at conservative and Strip the ball at aggressive for both sides which caused more fumbles and some of the best looking animations during tackles....