EDIT
Ok I found a workaround for multiplayer Position Locks.
Notice I said Position lock and not Player lock.
Player lock does not work with multiple players on one team. Only Position lock works.
Here's how to do it:
For Players 2, 3, 4 etc,
Go in to the Main Menu of 2K16. Then Features/Options.
Under Options > Controller Settings
Choose the position you want to lock on.
Do this for the other players as needed.
Once complete, start MyLeague/MyGM.
For Player 1 and ONLY player 1, go into Options > Position Settings and set the Position Lock.
Once complete, start the game and you'll see that everyone is locked on to their guy and will stay locked on to that position until the game is over.
NOTE - you can select Player lock for Player 1, however, since the game can't sim because of the other players locked on to their position, you're stuck being the main ball handler until your Player that you're locked on to comes back.
Hope this all makes sense.

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