KDRE,
If your regulars get killed, you get new regulars. However, they'll start out low-skilled (since you win attribute points after each mission). For the unlockable characters, if they die during the campaign, they're dead for the duration.
For the tank mission, I couldn't get through it without taking casualities. My recommendation is to keep one group in the canyon, lying prone (so snipers are a good choice) to start picking off the advancing troops. Move your other squad (with a rocket launcher soldier) up to the bridge, taking out the enemy soldiers up top, then get prone on the bridge. When the tanks are in range, switch control to the rocket launcher soldier, sit up, equip the launcher, and take the tanks out in a hurry before you get shot. (note: you can't get prone with the launcher equipped). This rocket launching skill will come in handy later, trust me...

And save often, at least after you complete each objective and right before you expect a big firefight.


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