Yea, it shouldn't make too much difference. The AI just won't have the shooting boosts and semi-cheating defense boosts that you'll see at SS/HOF.
I need that extra challenge from the CPU, or else I kind of lose focus/interest and start to play like crap.
Let me know how you like them! Most of the changes are to movement, animations, and fouls. Still need to tweak defense and offensive tendencies but that will take some time. The game plays pretty good at default, thankfully, so fixing the movement was my first concern.