As far as the sliders go, not only are they broken, but adjusting them effects players abilities. So you can crank up the holding slider and it won't give you more holding penalties, it may make your players block better, heck it might even make your QB less accurate, but its not going to give you more penalties.
Upping the PI slider won't give you any PI penalties, it will just make your DBs break on the ball better.
Its years upon years of broken code and incompetent programming layered ontop of eachother.