Depends on the QB, the offensive line and its blocking scheme and what the D is doing. We can go back to the Superbowl. On that first third down when Bruschi came on the blitz, McNabb had about 2 seconds if that. The blitz was timed and executed properly. When the defense relies on its front 4 against a line with good pass blocking the QB generally will have more time, unless you got a monster like Freeney out there who was on Kyle Boller within what 3 seconds
maybe less. So it depends I suppose. I'm for them killing nano BS, improving pass blocking schemes, but I'm not for those schemes to be impenetrable. If you've attacked it right and you have the athletes then don't penalize the guy on defense for anticipating correctly.