The thing is though, these plays that were mentioned aren't money plays. And your post suggests that same sentiment as well. You say that you can only have success by way of money plays, but go on to say that the defense knows exactly what is being called.
My suggestion is that you mix up the run, run inside, outside, counters, draws, and use play action pass. Some games you have to set up the run by throwing the ball. Sometimes its vice versa. I play with the Raiders who, at best, have an average offensive line and I can gain yardage on most plays. Sure I get knocked down in the back field occasionally, and sometimes I bust a 15+ yard run. Also, just because I call a stretch play, doesn't mean that I have to run outside. If I run a stretch play, and I see they are over pursuing to that side, then I look for a cutback lane. If I'm running up the middle and its clogged, I bounce outside, or at least try to. If I run 3 straight times to the right of my offensive line and then run a counter, usually its effective. Always? NO, but more often then not. Does it mean that I am going to rattle off a major gain? Again, no, but I usually can get 4+ yards which is a good average for any ball carrier.
Shifting the O-Line works as well. Also, I move TE's, FB's and WR's to try to either load up where I'm running, disguise where I'm running, or "unbalance" the defense to the side I'm running. Also, I am aware of who's who on defense. If there is run stopper or a good linebacker, I try to run away from them.
Honestly, its just doing whatever you can to keep the defense off balance.
I don't change sliders nor use the Madden IQ. I play on default All Madden, the same way I have for the last 10 years or so.
I am a diehard football fan as well. And I haven't traded it back in. And I'm not here to make excuses, just to offer advice. What enjoyment you get out of the game really makes no difference to me, because at the end of the day, I enjoy the game and thats priority number one. I am here to try and offer advice and insight as to how and why I have success running the ball or what have you. Either my advice/tips work for you or they don't. But I don't like being accused of making excuses for the game. I have no reason to. My account balance, enjoyment, nor fun factor changes or is influenced by what enjoyment others get out of the game. This site has offered me great tips and advice by way of variuous and numberous community members throughout my tenure here at OS. I am just trying to "arry on that tradition" and give something back.
-CB