I feel ya. Defenders reacting to the button press rather than the pass whether the slider is at 0, 50, or 100. Unable to complete passes to uncovered, completely wide open receivers because a defender warps 8-12 yards to break up the pass. If you try and put touch on anything, it's an automatic INT, even with the INT slider reduced.
I don't claim to be the world's best at NCAA, though I'm usually pretty good, but I cannot pass at all on AA. I'm not even going to try Heisman if it's anything like last year's.
Prior to NCAA 11 I always played on Heisman and I haven't played on Varsity in as long as I can remember, but I think I may have to drop down to Varsity and try to amp up the CPU through sliders. If I try to play any more on AA hoping to find the right CPU pass coverage slider I'm going to put my controller through my TV.
At this point, I'm not sure why EA even includes sliders because they are not working for me (and from reading in other threads, many others).