Yes! My wide receiver came second in the belitnikoff award voting with an 84 speed rating, 99 route running.
It's all how you play. If your offense consists only of deep throws go SPD and ACC. If you're too big a wimp to make timing passes and rely solely on slants and deep posts... Speed recruiters are probably the guys whining that hitch routes are broken.
It's all about your scheme. I go quick (not always fast) at HB with great juke and stiff arm. Great route runners at WR that can catch anything. Although I like having one guy that can force safeties to stay off.
I go fast on defensive backs, b+ or better with elite man cover skills. I leave them on an island in cover 1 or 0 most downs and want to know they will not be beat deep by anyone. This allows me to use overly physical lineman and backers, resulting in a stout run defense and plenty of sacks.
In short... It's all about what you do.
Oh also, I once tested SPD versus ACC. One WR with 97 SPD and 87 ACC and another with 92 SPD and 94 ACC. (if I'm remembering the exact numbers right) The WR with greater ACC jumped out to lead quick, just 1 or 2 yards. It took the WR with greater speed nearly 20 yards to catch up. Take from that what you will.