1) Nickel and dime sets.
2) Your 4-4 and Bear Package are great vs the run. Thing with the Bear package is the 3-0-3 linemen techniques are great verses inside runs but if the outside man gets beat on the outside its a good chance its going for 6.
Before you take up any defense in this game, it'll help you out to see how they're played in real life. Verses 3 wide receiver sets I like the Crash 2 blitz and I usually user the SS thats blitzing.
Here's another blitz that I created that TCU actually uses that you may wanna try.
Theres a bunch of great blitzes in this playbook but most of it actually playcalling and formation matching.