How many?

[BoomerSooner11]

Two..almost three..about four seasons into my Florida dynasty, I had recruited a dual threat QB and started him the following year, my RB got over a 100 as did my QB..the back up RB had like 93 yards I think..

[sportsgamer30]

four would be tough unless you do really long quarters. i like to pack up stats though....

[rwk2009]

I got 4 once. My starting QB and my first three HBs. I put the backups in at half if I'm destroying a team, and if I have a decent third stringer at a position he takes over for the backup at the start of the fourth quarter. 2nd & 3rd HB each had 100 yds in a quarter and starting QB & HB got over 100 each in the first half.
Felt great after the game =)

[marktg30]

With Washington State I had 2 RBs over 200 yards in a game. That is my best performance by far.

[canes21]

Four. I pu my fastest players in at RB and QB and just did options an entire game against DUKE in an OD. I am Miami