In addition to this, throw in some blitzes. Getting pressure on the QB can lead to him throwing the ball away. I would say it can lead to sacks, but we all know the computer has that knack to get rid of the ball just in time.
Also, play a mix of man and zone. Playing man all the time - you will eventually get beat esp if you are playing against an elite WR, plus I feel like it leads to fatigue of your DBs.
Watch your matchups and give extra help if there is one player consistently hurting you. Try spotlighting that receiver or using press coverage on him.