You can give these a whirl....
Skill: All American
Injuries/Fatigue: On
Quarter Length: 7 Minutes
Play Clock: On
Game Speed: Normal
Threshold: 40 (Set here to keep the long ball in check)
HFA/Ice Kicker: On
Offside:100
False Starts: 97
Holding: 53
Facemask: 55
OPI: 100
DPI: 100
KR/
PR Interf: 100
Clipping: 54
Int Grounding: 52 (Set here because the QB will throw the ball away and not just stand there and take a sack. Besides I don't think I have ever recalled a penalty for this anyway.)
Roughing Passer: 54
Roughing Kicker: 100
Both User and CPU
QBA: 55 (This allows for a higher completion percentage and he will still throw floaters down field)
PB: 55
WRC: 40 (They still will drop some easy ones from time to time but also has a tendency to drop balls when they get nailed)
RBA: 55
RB: 55
PC: 55 (This one was a tuffy, but decided with this number because your frequency of getting beat on the long ball is greatly reduced and you short passes are covered. Now I also noticed that since it's tighter coverage, you'll still complete passes but they defense won't be sooooo out of position.
PR: 45
INT: 25
RD: 45
TKL: 45 (Still will miss a tackle from time to time but you ain't gonna see a 178lb RB bowl over a 300lb DT)
FGP: 50
FGA: 35 (The accuracy of a real college kicker at 40+yds is aweful)
PP: 45
PA: 35
KOP: 50
I find playing in dynasty mode is different than play now. In my humble opinion the game seems to work better on play now than dynasty. Just my opinion.