Ahh this brings me to my near upset of Missouri, year one with the University of North Dakota(via teambuilder). It's not the absolute worst thing, but it was an unfortunate event.
I was down 24-3 at the half, getting my butt kicked. I was able to turn the game upside down in the second half and make the score 33-27, Mizzou, with just under a minute to go. I need a TD + extra point to win.
I drive down and get near the 50, clock stopped at :30. Everything's goin my way and I run a corners play. I have a WR one on one and he's got his man beat. But my QB underthrows it(IDK how really) and it gets picked.
End of game.
Another game I played in the dynasty I ended up turning the ball over 7 times. That was just the worst game ever.