I played through again recently on PC and it looks damn good. Hair works off, Ultra settings except for Shadows and Foliage Visibility Range on High, locked at 30fps with NV Inspector and Rivatuner. Your 390 will probably do the same, but at 60fps or you could push beyond Ultra settings with ini tweaks and lock it at 30fps. The in-game vsync and frame rate limiter gives bad frame pacing, so do it through the GPU driver.
It's a good looking game on console, but textures, shadows, draw distance, foliage density, water, effects, and load times are noticeable improvements on PC.
I used these two mods:
http://www.nexusmods.com/witcher3/mods/365/?
http://www.nexusmods.com/witcher3/mods/347/?

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