I'm using 3, as per the 6.01 Alpha settings.
The only bits I've altered are in bold:
Playcall Style: Slim or Enhanced (VERY important - see house rule)
Speed: Slow or Normal (I prefer slow)
Gameplay: All Madden
qtr length: 13min
accel clock: 18 sec
injuries: 57
fatigue: 70
speed threshold:
3 instead of 1.
ball hawk: off
strafe assist: off
heat seeker assist: off
switch assist: off
Defensive Graphics: off, user preference
Camera: Standard, user preference
HUM
qb acc: 6 (modify to get the challenge you desire)
pass blocking: 35
wr catching: 48
run blocking: 5
Fumbles: 40
Reaction time: 50
Interceptions:
30 instead of 35
Pass coverage: 30
tackling: 27
CPU
qb acc: 3
pass blocking: 3
wr catching: 48
run blocking:
20 instead of 15
Fumbles: 40
Reaction time: 50
Interceptions:
30 instead of 35
Pass coverage: 30
tackling: 27
Special Teams
FG Power – 50/50
FG Acc - 30/30
Punt Power - 45/45
Punt Acc - 75/75
KO Power - 52/53
Penalties
Offside: 50
False Start:70
Holding: 70
Facemask: 40
DPI: 98
OPI: 99
PCI: 36 (use 35 if you want a more offensively-oriented game)
I'm using 35 here, though I've ZERO idea what this is about or what it effects
Clipping: 50
int grounding: 57 (VERY important - need to modify if you change CPU QBA or threshold)
roughing the passer:50 (was at 10)
roughing the kicker: 30
Autosubs (In/Out)
QB - 0/2
HB - 91/96
WR - 20/25
TE - 30/35
OL - 0/2
DL - 80/85
LB - 50/55
CB - 20/25
S - 25/30