This thread moves quickly....lol.
But, I tested the OP set with the 45/50 Run Frequency, 54/54 pass error, and 51/51 Shot Speed. Looked good.
Tried the 35/35 GKA...really odd over several matchups...issues mainly with the CPU attack.
It's almost like the CPU said "Oh, their GK is weak, we don't have to try so hard". So, they batted the ball around more, more build-up (not a bad thing), and fewer driven passes (again, not a bad thing). But I really noticed that in the box on many occassions, the attacker would dribble right up to the GK before shooting or try for the "perfect pass". It also felt a little less physical. Again, this was with the OP with the other three adjustments.
As a quick experiment, I reset all the sliders to default but lowered GKA to 10/10 (testing extremes). The CPU built-up more and used the driven pass a bit less (i.e. they were less direct) than they otherwise would've been at a pure default setup.
So, there would appear to be an underpinning change in the dynamics with going too extreme here (at least from what I observed).
Not necessarily advocating one thing over another...just providing observations